Preheat the oven to 425°F and line a baking sheet or pizza pan with parchment paper.
Add the cauliflower florets to a food processor and pulse until they resemble fine rice. Transfer the riced cauliflower to a large skillet and cook over medium heat for 6–8 minutes, stirring frequently, until softened and any excess moisture has cooked off. Remove from heat and let cool slightly.
Transfer the cooked cauliflower to a clean kitchen towel and squeeze out as much liquid as possible. This step is key for a firm crust.
In a mixing bowl, combine the drained cauliflower, egg, salt, oregano, Parmesan cheese, and minced garlic. Stir until fully combined.
Press the mixture onto the prepared baking sheet in a thin, even circle about ¼-inch thick. Bake for 20–22 minutes, or until the crust is golden and set.
Remove from the oven and spread marinara sauce over the crust. Sprinkle with mozzarella and arrange pepperoni on top.
Return to the oven for 7–10 minutes, or until the cheese is melted and bubbly. Let cool slightly before slicing and serving.
Remove as much moisture as possible: This is the most important step for a firm cauliflower pizza crust. After cooking the cauliflower, let it cool slightly, then squeeze it very well using a clean kitchen towel or cheesecloth.
Use parchment paper: Cauliflower crust sticks easily. Parchment ensures easy removal and clean slicing.
Press evenly: Aim for an even thickness across the crust, especially in the center, so it bakes through without becoming soft.
Don’t overload the toppings: Too much sauce or cheese can weigh the crust down and make it soggy. Keep toppings light for best results.
Let it rest before slicing: Allow the pizza to cool for 3–5 minutes after the final bake so the crust sets and slices cleanly.
Best served fresh: Cauliflower pizza crust is at its firmest right out of the oven and softens as it sits.